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Table 1 The major amino acid substitutions among the seven related strains of DENV-3 from China, Laos, India and Singapore as compared with the standard strain H87

From: Molecular characterization and phylogenetic analysis of a dengue virus serotype 3 isolated from a Chinese traveler returned from Laos

Aa position H87 YNPE3 Balotra87_s YN01 UI17760 D3/SG/CT7/2012
Philippines 1956 China 2013 India 2013 China 2013 Laos 2010 Singapore 2012
GV GIII GIII GII GII GI
ORF Protein       
Capsid
 35 35 R K K    
 86 86 K R     
 108 108 M I I    
Envelope
 361 81 I V V    T
 404 124 S L P    L
 412 132 H Y Y    
 420 140 I    T T  
 434 154 E    D D  
 444 164 S P P P P  
 449 169 A T T V V P
 505 225 K E E E E V
 550 270 T N N N N E
 551 271 T S S S S T
 572 292 K E E E E S
 581 301 L T T    E
 663 383 K N N    S
 671 391 R K K K K  
 727 447 S    G G K
 732 452 I V V    
NS1
 820 47 R K     
 821 48 V L L L L L
 856 83 D N N N N N
 866 93 I T T    
 867 94 T I I I I I
 871 98 E D     
 893 120 L K K K K K
 912 139 S N N N N N
 951 178 L M M T T L
 961 188 V    I I  
 990 217 L    F F  
 1029 256 H Y Y    Y
 1061 288 S T T T T T
 1112 339 N S S    
NS2A
 1162 37 L F F    
 1225 100 E K     
 1237 112 A T T T T T
 1240 115 R Q Q Q Q Q
 1267 142 T I     
 1275 150 V I I    
 1300 175 I V V V V  
NS3
 1504 31 F L L    
 1588 115 I T T    
 1829 356 V A A    
 1865 392 D E E    
 1910 437 D E     
 1925 452 V A A A A  
 1949 476 M T T   T T
 1962 489 W E     
 1964 491 E Q     
 1965 492 A E     
 2041 568 E Q Q    
NS4A
 2162 70 L I     
 2191 99 D E E    
 2192 100 V I I    I
 2240 148 V I I    
NS4B
 2357 115 V I I    
 2393 151 M I I    
NS5
 2540 50 I T T T T  
 2678 188 T A A    A
 2778 288 S N N    
 2912 422 R K K    
 3052 562 Q L L    
 3075 585 K T T    
 3109 619 I V V    
 3129 639 L P P    
 3130 640 E G     A
 3253 763 T S S S S  
 3325 835 D N N    
 3354 864 L S P    
  1. The GI, GII, GIII and GV represent genotype I, genotype II, genotype III and genotype V, respectively. The accession number of those related strains: H87(M93130), Balotra87_s(KU216209), YN01(KF824902), UI17760(KY849769), D3/SG/CT7/2012(KX380839). YNPE3(MF370226)