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Table 1 Demographics, clinical characteristics, and serum sample availability for 14 Zika and 60 dengue cases confirmed by RT-PCR

From: Diagnostic performance of commercial IgM and IgG enzyme-linked immunoassays (ELISAs) for diagnosis of Zika virus infection

Characteristics

Zika cases (N = 14)

Dengue cases (N = 60)

Number (%) or median (interquartile range)

Demographic

 Male

6 (42.9)

31 (51.7)

 Age

22.5 (15–41)

18 (10–34)

Clinical Manifestations

 Headache

13 (92.9)

58 (96.7)

 Myalgia

12 (85.7)

46 (76.7)

 Retro-orbital pain

10 (71.4)

34 (56.7)

 Arthralgia

8 (57.1)

28 (46.7)

 Vomit

2 (14.3)

12 (20.0)

 Rash

10 (71.4)

6 (10.0)

 Pruritus

10 (71.4)

NA

Prior dengue infectiona

 No

1 (8.3)

13 (21.7)

 Yes

11 (91.7)

47 (78.3)

Blood sample collected

 Acute-phase sample

14 (100)

60 (100)

  Time between symptoms onset and sample collection

2.5 (2–4)

2 (1–3)

 Convalescent-phase sample

8 (57.1)

60 (100)

  Time between symptoms onset and sample collection

27 (18.5–43.5)

27 (19.5–57.5)

Sera tested by ZIKV ELISAb

 ZIKV IgM-ELISA in acute-phase sera

14 (100)

58 (96.7)

 ZIKV IgM-ELISA in convalescent-phase sera

8 (57.1)

59 (98.3)

 ZIKV IgG-ELISA in acute-phase sera

13 (92.9)

NT

 ZIKV IgG-ELISA in convalescent-phase sera

8 (57.1)

60 (100)

  1. NT = Not tested
  2. aPrior dengue infection was determined by a positive result in the DENV IgG-ELISA performed in the acute-phase serum sample
  3. bSome patients did not have their acute- or convalescent serum sample tested for ZIKV because of insufficient volume of sera