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Table 5 The frequencies of the 7 MHC-DRB1 alleles in M. himalayana from the 4 areas with different susceptibility to WHV infection

From: Chinese woodchucks with different susceptibility to WHV infection differ in their genetic background exemplified by cytochrome B and MHC-DRB molecules

WHV susceptibility

Area

n.

The frequency of the Mamo-DRB1 alleles (%)

*01

*02

*03

*04

*05

*06

*07

High replication pattern

TR

9

22.22

(2/9)

77.78

(7/9)

11.11

(1/9)

11.11

(1/9)

11.11

(1/9)

22.22

(2/9)

/

TD

2

/

50.00

(1/2)

/

/

/

/

50.00

(1/2)

Total

11

18.18

(2/11)

72.73

(8/11)

9.09

(1/11)

 

9.09

(1/11)

18.18

(1/11)

9.09

(1/11)

Low replication pattern

GD

3

/

33.33

1/3

/

/

/

33.33

(1/3)

66.66

(2/3)

WL

5

/

40.44

2/5

/

/

20.00

1/5

/

40.00

(2/5)

Total

8

/

37.50

3/8

/

/

12.5

1/8

12.5

(1/8)

50.00

(4/8)

Total

19

10.53

2/19

57.89

11/19

5.26

1/19

5.26

1/19

10.53

2/19

10.53

2/19

26.32

5/19

  1. The MHC class II DRB1 sequences from 19 Chinese woodchucks were obtained, 9 from TR area, 2 from TD area, 3 from GD area, and 5 from WL area. The frequencies of the 7 MHC-DRB1 alleles in the animals from the four areas were compared