HPV-16, HPV-58, and HPV-33 are the most carcinogenic HPV genotypes in Southwestern China and their viral loads are associated with severity of premalignant lesions in the cervix

Table 3 Correlation analyses of the relationships between HPV DNA load and patient age and the severity of intraepithelial lesions

Genotype	CC with patient age	P value	CC with lesion severity	P value
HPV-16	0.041	0.425	0.121^*	0.016
HPV-18	−0.182	0.08	−0.104	0.322
HPV-31	−0.041	0.715	0.071	0.523
HPV-33	0.003	0.978	0.209^*	0.026
HPV-35	−0.143	0.198	−0.025	0.822
HPV-39	− 0.167	0.053	0.026	0.768
HPV-45	−0.025	0.886	− 0.083	0.637
HPV-51	−0.14	0.868	0.124	0.134
HPV-52	−0.019	0.674	0.088	0.057
HPV-56	0.22	0.03	0.025	0.804
HPV-58	0.102^*	0.027	0.189^**	< 0.001
HPV-59	−0.228^*	0.022	−0.068	0.5
HPV-68	−0.032	0.707	−0.032	0.706
Total HPV	−0.008	0.714	0.143^**	< 0.001

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