HPV-16, HPV-58, and HPV-33 are the most carcinogenic HPV genotypes in Southwestern China and their viral loads are associated with severity of premalignant lesions in the cervix

Table 2 Distribution of the 13 High-risk Human papillomavirus (HR-HPV) genotypes according to final diagnoses among the 1728 HPV infected patients

Genotype	Normal cervix	Inflammation	CINI	CINII	CINIII	ICC	Others	Total	Rate (%)	χ² value	P value
HPV-56	39	38	8	1	3	1	8	98	4.38	/	/
HPV-16	119	104	22	20	78	41	12	396	17.69	36.91^**	< 0.001
HPV-18	34	36	5	2	5	5	6	93	4.15	4.74	0.691
HPV-31	24	37	3	2	10	1	6	83	3.71	9.07	0.248
HPV-33	34	29	5	14	20	4	8	114	5.09	26.82^**	< 0.001
HPV-35	31	30	4	3	7	0	8	83	3.71	5.58	0.589
HPV-39	56	54	10	3	3	1	8	135	6.03	1.20	0.991
HPV-45	15	13	3	1	1	0	2	35	1.56	1.23	0.990
HPV-51	60	65	11	7	2	1	2	148	6.61	10.58	0.158
HPV-52	186	201	29	20	16	2	18	472	21.08	7.01	0.427
HPV-58	90	136	31	19	42	10	14	342	15.27	18.22^**	0.009
HPV-59	36	46	6	2	5	1	5	101	4.51	2.65	0.915
HPV-68	60	58	7	4	3	1	6	139	6.21	3.79	0.803

^**The significance is at the P ≤ 0.01 level. The data of HPV-56 is employed as test control

ISSN: 1743-422X