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Table 1 Distribution of the 13 High-risk Human papillomavirus (HR-HPV) infection according to final diagnoses among the 7747 patients

From: HPV-16, HPV-58, and HPV-33 are the most carcinogenic HPV genotypes in Southwestern China and their viral loads are associated with severity of premalignant lesions in the cervix

Diagnosis Infected (%) Negative (%) Total χ2value P value
Normal cervix 628 (19.84) 2537 (80.16) 3165 / /
Inflammation 644 (18.04) 2926 (81.96) 3570 3.56 0.169
CINI 104 (48.37) 111 (51.63) 215 96.58** < 0.001
CINII 73 (61.34) 46 (38.66) 119 117.66** < 0.001
CINIII 148 (70.81) 61 (29.19) 209 287.62** < 0.001
ICC 59 (78.67) 16 (21.33) 75 151.74** < 0.001
Others 72 (18.27) 322 (81.73) 394 0.55 0.761
Total 1728 (22.31) 6019 (77.69) 7747 8.05* 0.018
  1. Normal cervix is served as test control. Normal cervix describes those who are negative for intraepithelial lesions or malignancy and do not have inflammation or other benign lesions; Inflammation describes those with inflammatory or other benign lesions, including chronic cervicitis, cervical hypertrophy, nabothian cysts, erosion, bleeding, and hyperplasia. CINI describes cervical intraepithelial neoplasia grade I (low dysplasia), corresponding to LSIL. CINII and CINIII describe cervical intraepithelial neoplasia grade II (moderate dysplasia) and III (severe dysplasia), respectively, corresponding to HSIL. ICC describes invasive cervical cancer, whereas others describe cases after surgery or treatment of hysteromyoma, and so on
  2. **The significance is at the P ≤ 0.01 level
  3. *The significance is at the P ≤ 0.05 level