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Table 1 Distribution of the 13 High-risk Human papillomavirus (HR-HPV) infection according to final diagnoses among the 7747 patients

From: HPV-16, HPV-58, and HPV-33 are the most carcinogenic HPV genotypes in Southwestern China and their viral loads are associated with severity of premalignant lesions in the cervix

Diagnosis

Infected (%)

Negative (%)

Total

χ2value

P value

Normal cervix

628 (19.84)

2537 (80.16)

3165

/

/

Inflammation

644 (18.04)

2926 (81.96)

3570

3.56

0.169

CINI

104 (48.37)

111 (51.63)

215

96.58**

< 0.001

CINII

73 (61.34)

46 (38.66)

119

117.66**

< 0.001

CINIII

148 (70.81)

61 (29.19)

209

287.62**

< 0.001

ICC

59 (78.67)

16 (21.33)

75

151.74**

< 0.001

Others

72 (18.27)

322 (81.73)

394

0.55

0.761

Total

1728 (22.31)

6019 (77.69)

7747

8.05*

0.018

  1. Normal cervix is served as test control. Normal cervix describes those who are negative for intraepithelial lesions or malignancy and do not have inflammation or other benign lesions; Inflammation describes those with inflammatory or other benign lesions, including chronic cervicitis, cervical hypertrophy, nabothian cysts, erosion, bleeding, and hyperplasia. CINI describes cervical intraepithelial neoplasia grade I (low dysplasia), corresponding to LSIL. CINII and CINIII describe cervical intraepithelial neoplasia grade II (moderate dysplasia) and III (severe dysplasia), respectively, corresponding to HSIL. ICC describes invasive cervical cancer, whereas others describe cases after surgery or treatment of hysteromyoma, and so on
  2. **The significance is at the P ≤ 0.01 level
  3. *The significance is at the P ≤ 0.05 level