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Table 1 Appearance of anti-HBs antibody at indicated time points AHI with different HBV plasmids DNA

From: The doses of plasmid backbone plays a major role in determining the HBV clearance in hydrodynamic injection mouse model

HBV plasmid Week 1–3 Week 4 Week 5 Week 11
6 μg WT pAAV/HBV1.2 0/20 0/20 0/20 5/20
20 μg WT pAAV/HBV1.2 0/20 0/20 4/20 16/20
20 μg e/core-null pAAV/HBV1.2 0/10 1/10 3/10 10/10
6 μg WT pAAV/HBV1.2
plus 14 μg pAAV/Control
0/20 1/20 5/20 18/20
  1. The number of mice in each group positive for anti-HBs antibody