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Table 1 Appearance of anti-HBs antibody at indicated time points AHI with different HBV plasmids DNA

From: The doses of plasmid backbone plays a major role in determining the HBV clearance in hydrodynamic injection mouse model

HBV plasmid

Week 1–3

Week 4

Week 5

Week 11

6 μg WT pAAV/HBV1.2

0/20

0/20

0/20

5/20

20 μg WT pAAV/HBV1.2

0/20

0/20

4/20

16/20

20 μg e/core-null pAAV/HBV1.2

0/10

1/10

3/10

10/10

6 μg WT pAAV/HBV1.2

plus 14 μg pAAV/Control

0/20

1/20

5/20

18/20

  1. The number of mice in each group positive for anti-HBs antibody