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Fig. 1 | Virology Journal

Fig. 1

From: The doses of plasmid backbone plays a major role in determining the HBV clearance in hydrodynamic injection mouse model

Fig. 1

The doses of pAAV/HBV1.2 plasmid determine HBV persistence in C57BL/6 mice. C57BL/6 mice were hydrodynamically injected with 6 μg or 20 μg pAAV/HBV1.2 plasmid. Serum levels of HBsAg (a) and HBeAg (b) were measured at indicated time points. c Positive rate of serum HBsAg after HBV plasmid injection. d Immunohistochemical staining for HBcAg in liver sections of mice at week 6 after injection with 6 μg or 20 μg pAAV/HBV1.2 plasmid. (original magnification: 100×). Results represent 2 independent experiments (n = 10/group)

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Virology Journal

ISSN: 1743-422X