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Table 1 Sensitivity, specificity and over all agreement with real time RT-PCR of immunochromatography kit for chikungunya virus antigen using clinical serum samples in various clinical categories

From: Evaluation of an immunochromatography rapid diagnosis kit for detection of chikungunya virus antigen in India, a dengue-endemic country

  Criteria of CHIKV positive Sensitivity (%) Specificity (%) OAA*1 (%)
Group 1*2 qRT-PCR or IgM qRT-PCR and/or IgM 72.1 (75/104) 94.7 (18/19) 75.6
Group 2 qRT-PCR 93.7 (74/79) 95.5 (42/44) 94.3
Group 3 IgM 46.0 (23/50) 27.4 (20/73) 35.0
Group 4 qRT-PCR and IgM 88.0 (22/25) 44.9 (44/98) 53.7
  1. The sensitivity, specificity and overall agreement of IC kit were calculated using qRT-PCR as a gold standard. *1 OAA: Overall agreement with real time RT-PCR. * [2] Group 1 includes three groups, qRT-PCR and IgM positive group, either qRT-PCR positive or IgM positive