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Table 1 Sensitivity, specificity and over all agreement with real time RT-PCR of immunochromatography kit for chikungunya virus antigen using clinical serum samples in various clinical categories

From: Evaluation of an immunochromatography rapid diagnosis kit for detection of chikungunya virus antigen in India, a dengue-endemic country

 

Criteria of CHIKV positive

Sensitivity (%)

Specificity (%)

OAA*1 (%)

Group 1*2

qRT-PCR or IgM

qRT-PCR and/or IgM

72.1

(75/104)

94.7

(18/19)

75.6

Group 2

qRT-PCR

93.7

(74/79)

95.5

(42/44)

94.3

Group 3

IgM

46.0

(23/50)

27.4

(20/73)

35.0

Group 4

qRT-PCR and IgM

88.0

(22/25)

44.9

(44/98)

53.7

  1. The sensitivity, specificity and overall agreement of IC kit were calculated using qRT-PCR as a gold standard. *1 OAA: Overall agreement with real time RT-PCR. * [2] Group 1 includes three groups, qRT-PCR and IgM positive group, either qRT-PCR positive or IgM positive
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Virology Journal

ISSN: 1743-422X