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Table 1 Sensitivity, specificity and over all agreement with real time RT-PCR of immunochromatography kit for chikungunya virus antigen using clinical serum samples in various clinical categories

From: Evaluation of an immunochromatography rapid diagnosis kit for detection of chikungunya virus antigen in India, a dengue-endemic country

  Criteria of CHIKV positive Sensitivity (%) Specificity (%) OAA*1 (%)
Group 1*2 qRT-PCR or IgM
qRT-PCR and/or IgM
72.1
(75/104)
94.7
(18/19)
75.6
Group 2 qRT-PCR 93.7
(74/79)
95.5
(42/44)
94.3
Group 3 IgM 46.0
(23/50)
27.4
(20/73)
35.0
Group 4 qRT-PCR and IgM 88.0
(22/25)
44.9
(44/98)
53.7
  1. The sensitivity, specificity and overall agreement of IC kit were calculated using qRT-PCR as a gold standard. *1 OAA: Overall agreement with real time RT-PCR. * [2] Group 1 includes three groups, qRT-PCR and IgM positive group, either qRT-PCR positive or IgM positive