Fig. 5
Effect of CST on the inhibition of proinflammatory cytokine production and COX-2 protein expression in THP-1 cells. a, b, c and d THP-1 cells were infected with 100TCID50 IAV and treated with 10 μg/ml of CST for 6 h. The IL-1β, TNF-α, IL-8, and IL-10 mRNA levels were determined by qRT-PCR. **p < 0.01 significantly different from the Con group. Data are expressed as mean ± SD, and the results represent the average findings of three independent experiments. e THP-1 cells were infected with 100TCID50 IAV in the presence or absence of CST of different concentrations and RBV for 18 h