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Table 4 Receiver operating characteristic curve analysis for predicting HBsAg clearance

From: Pretreatment microRNA levels can predict HBsAg clearance in CHB patients treated with pegylated interferon α-2a

Variables Specificity (%) Sensitivity (%) PPV (%) NPV (%) AUC YI Best Cut-off p
miR-3960 93.33 64.71 84.62 82.35 0.8333 0.624 18.96
miR-126-3p 86.67 35.29 60.00 70.27 0.7510 0.557 8.64
miR-335-5p 90.00 41.18 70.00 72.97 0.7294 0.388 15.67
miR-23a-3p 83.33 11.76 28.57 62.50 0.6275 0.331 14.24
miR-3960 + miR-126-3p 96.67 70.59 92.31 85.29 0.8529 0.673 0.567a
  1. PPV positive predict value, NPV negative predict value, AUC area under curve, YI Youden index
  2. acompared with AUC of miR-3960