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Table 4 Receiver operating characteristic curve analysis for predicting HBsAg clearance

From: Pretreatment microRNA levels can predict HBsAg clearance in CHB patients treated with pegylated interferon α-2a

Variables

Specificity (%)

Sensitivity (%)

PPV (%)

NPV (%)

AUC

YI

Best Cut-off

p

miR-3960

93.33

64.71

84.62

82.35

0.8333

0.624

18.96

–

miR-126-3p

86.67

35.29

60.00

70.27

0.7510

0.557

8.64

–

miR-335-5p

90.00

41.18

70.00

72.97

0.7294

0.388

15.67

–

miR-23a-3p

83.33

11.76

28.57

62.50

0.6275

0.331

14.24

–

miR-3960 + miR-126-3p

96.67

70.59

92.31

85.29

0.8529

0.673

–

0.567a

  1. PPV positive predict value, NPV negative predict value, AUC area under curve, YI Youden index
  2. acompared with AUC of miR-3960
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Virology Journal

ISSN: 1743-422X