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Fig. 2 | Virology Journal

Fig. 2

From: The truncated mutant HBsAg expression increases the tumorigenesis of hepatitis B virus by regulating TGF-β/Smad signaling pathway

Fig. 2

The gross pathological and histopathological changes of xenografts in nude mouse. a Nude mice injected with HBV replication L02 cell lines stably expressing wild type, substitute and truncated HBsAg, respectively; (b) nude mice injected with L02 cell lines stably expressing wild type, substitute and truncated HBsAg, respectively. The tumor volume was significantly higher in nude mice with pHBV4.1-HBs(sW172*) or pcDNA3.1-HBs(sW172*) as compared to other groups

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