Fig. 1From: The truncated mutant HBsAg expression increases the tumorigenesis of hepatitis B virus by regulating TGF-β/Smad signaling pathwayFormation of colonies in soft agar. The ratio of cell clones were less than 30% in L02-pHBV4.1-HBs(wt) (a) and L02-pHBV4.1-HBs(sW172L) (b), but well formed with a ratio of 60% in L02-pHBV4.1-HBs(sW172*) cell clones (c). Though the ratio of cell clones were less than 20% in either L02-pcDNA3.1 (d), L02-pcDNA-HBs(wt) (e), L02-pcDNA-HBs(sW172L) (f) and L02-pcDNA-HBs(sW172*) (g), the ratio of cell clones was more in L02-pcDNA-HBs(sW172*) than in other three groupsBack to article page