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Table 4 Analysis on the associations between SNPs selected from GWAS and anti-HEV IgG seropositivity

From: Evaluation of candidate genes associated with hepatitis A and E virus infection in Chinese Han population

Gene nomenclature

SNP

Anti-HEV IgG

WT/HT/MT

OR(95%CI)a

Additive

Dominant

Recessive

APOA4

rs1268354

 

CC/CT/TT

   

Positive

341/413/129

0.929(0.828–1.043)

0.88(0.748–1.034)

0.967(0.775–1.208)

Negative

778/1083/324

P = 0.212

P = 0.121

P = 0.77

APOE

rs405509

 

TT/TG/GG

   

Positive

443/377/62

0.996(0.88–1.127)

1.035(0.884–1.211)

0.863(0.639–1.166)

Negative

1120/886/182

P = 0.944

P = 0.67

P = 0.337

rs7412

 

CC/CT/TT

   

Positive

757/122/6

0.853(0.694–1.049)

0.831(0.668–1.034)

1.148(0.433–3.044)

Negative

1820/360/13

P = 0.131

P = 0.098

P = 0.781

rs769450

 

AA/AG/GG

   

Positive

556/300/29

1.044(0.909–1.2)

1.091(0.927–1.284)

0.831(0.542–1.274)

Negative

1426/677/90

P = 0.542

P = 0.292

P = 0.395

  1. WT wild type, HT heterozygote, MT mutant type
  2. a: Adjusted for age and sex