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Table 3 Gender-stratification analysis on the association between selected SNPs and anti-HAV seropositivity

From: Evaluation of candidate genes associated with hepatitis A and E virus infection in Chinese Han population

Gene nomenclature

SNP

Stratum

Anti-HAV IgG

WT/HT/MT

OR(95%CI)/P valuea

Additive

Dominant

Recessive

CAT

rs769214

  

GG/GA/AA

   

Male

positive

654/525/115

0.955(0.797–1.144)

0.920(0.727–1.163)

1.019(0.673–1.544)

 

negative

172/152/31

P = 0.618

P = 0.485

P = 0.928

Female

positive

536/450/86

0.994(0.822–1.201)

1.000(0.786–1.273)

0.965(0.622–1.498)

negative

175/146/29

P = 0.946

P = 1.000

P = 0.875

XRCC1

rs1001581

  

AA/AG/GG

   

Male

positive

491/577/229

0.911(0.774–1.073)

0.824(0.644–1.055)

0.978(0.720–1.328)

 

negative

119/173/64

P = 0.266

P = 0.125

P = 0.888

Female

positive

438/463/174

0.925(0.781–1.096)

0.842(0.656–1.081)

1.010(0.727–1.404)

negative

128/165/56

P = 0.369

P = 0.177

P = 0.951

ABCB1

rs1045642

  

CC/CT/TT

   

Male

positive

497/624/174

0.848(0.714–1.007)

0.827(0.646–1.059)

0.773(0.561–1.067)

 

negative

120/174/59

P = 0.061

P = 0.131

P = 0.117

Female

positive

416/483/172

0.900(0.759–1.067)

0.879(0.684–1.129)

0.852(0.621–1.169)

negative

125/160/64

P = 0.224

P = 0.312

P = 0.321

TGFβ1

rs1800469

  

CC/CT/TT

   

Male

positive

350/637/307

0.910(0.771–1.074)

0.820(0.623–1.079)

0.947(0.721–1.244)

 

negative

83/185/88

P = 0.265

P = 0.156

P = 0.697

Female

positive

250/557/265

0.947(0.796–1.127)

0.962(0.721–1.283)

0.904(0.687–1.190)

negative

79/177/93

P = 0.542

P = 0.792

P = 0.471

CYP2E1

rs2031920

  

CC/CT/TT

   
 

Male

positive

795/438/61

0.865(0.712–1.051)

0.868(0.684–1.102)

0.714(0.435–1.171)

negative

206/126/23

P = 0.144

P = 0.244

P = 0.180

Female

positive

676/342/52

0.860(0.702–1.052)

0.810(0.633–1.037)

0.938(0.542–1.628)

negative

203/128/18

P = 0.142

P = 0.094

P = 0.823

  1. WT wild type, HT heterozygote, MT mutant type
  2. a Adjusted for age