Table 2 Analysis on the association between SNPs selected from GWAS and anti-HAV IgG seropositivity
Gene nomenclature | SNP | Anti-HAV IgG | WT/HT/MT | OR(95%CI)a | ||
|---|---|---|---|---|---|---|
Additive | Dominant | Recessive | ||||
CAT | rs769214 | GG/GA/AA | ||||
Positive | 1190/975/201 | 0.979(0.858–1.117) | 0.966(0.815–1.144) | 1.000(0.738–1.355) | ||
Negative | 347/298/60 | P = 0.754 | P = 0.687 | P = 0.999 | ||
XRCC1 | rs1001581 | AA/AG/GG | ||||
Positive | 929/1040/403 | 0.920(0.817–1.036) | 0.836(0.700–0.998) | 0.995(0.794–1.247) | ||
Negative | 247/338/120 | P = 0.168 | P = 0.047 | P = 0.966 | ||
ABCB1 | rs1045642 | CC/CT/TT | ||||
Positive | 913/1107/346 | 0.862(0.763–0.974) | 0.835(0.699–0.997) | 0.802(0.638–1.007) | ||
Negative | 245/334/123 | P = 0.017 | P = 0.047 | P = 0.057 | ||
TGFβ1 | rs1800469 | CC/CT/TT | ||||
Positive | 600/1194/572 | 0.918(0.813–1.037) | 0.878(0.719–1.073) | 0.908(0.747–1.104) | ||
Negative | 162/362/181 | P = 0.169 | P = 0.204 | P = 0.332 | ||
CYP2E1 | rs2031920 | CC/CT/TT | ||||
Positive | 1471/780/113 | 0.868(0.754–1.001) | 0.851(0.716–1.012) | 0.799(0.551–1.159) | ||
Negative | 409/254/41 | P = 0.051 | P = 0.068 | P = 0.237 | ||