Fig. 4
From: Inhibition of HIV early replication by the p53 and its downstream gene p21
Comparative Analysis of p21, SAMHD1, pSAMHD1 (T592) and RNR2 between non-cycling HCT116 p53+/+ cells and non-cycling HCT116 p53−/− cells in HIV-1 infection. a Western blot of p21, SAMHD1, pSAMHD1 (T592) and RNR2 between non-cycling HCT116 p53+/+ cells and non-cycling HCT116 p53−/− cells in HIV-1 infection. b Quantitative analysis of p21 protein between non-cycling HCT116 p53+/+ cells and non-cycling HCT116 p53−/− cells in HIV-1 infection. c Quantitative analysis of SAMHD1 protein between non-cycling HCT116 p53+/+ cells and non-cycling HCT116 p53−/− cells in HIV-1 infection. d Quantitative analysis of pSAMHD1 (T592) protein between non-cycling HCT116 p53+/+ cells and non-cycling HCT116 p53−/− cells in HIV-1 infection. e Quantitative analysis of RNR2 protein between non-cycling HCT116 p53+/+ cells and non-cycling HCT116 p53−/− cells in HIV-1 infection. The results represented a duplicate experiment. In Student’s t-test, p value < 0.05 is indicated by *; p value < 0.01 is indicated by **