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Table 1 Growth on receptor-deficient cells and neutralization profiles of A24 Cruzeiro and O1 Manisa and their derivatives

From: Influence of cell type and cell culture media on the propagation of foot-and-mouth disease virus with regard to vaccine quality

Virus isolate

Cell line

VNT

CHO-K1

CHO677

Serum titer

r1-value

A24 Cruzeiro

2.8 ± 0.2

negative

3.4 ± 0.2

 

A24–179

2.3 ± 0.3

negative

3.6 ± 0.2

1.05

A24-2P

4.0 ± 0.4

2.5 ± 0.6

3.5 ± 0.1

1.02

O1 Manisa

2.8 ± 0.1

negative

3.2 ± 0.1

 

O1–179

2.0 ± 0.1

negative

3.5 ± 0.2

1.09

O1-2P

1.9 ± 0.2

negative

3.4 ± 0.1

1.06

  1. Values represent mean virus and neutralization titers and standard deviations, shown as log10 infectious or neutralizing doses per milliliter. The r1-value was calculated by dividing the neutralization titer against the adapted isolate by the neutralization titer against the original virus isolate
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Virology Journal

ISSN: 1743-422X