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Table 3 Logistic regression of each polymorphism in cases (chronic HCV-infected patients) versus controls (uninfected individuals)

From: IL28B gene polymorphism rs12979860, but not rs8099917, contributes to the occurrence of chronic HCV infection in Uruguayan patients

Factor

Univariable Models

Multivariable Model

Estimate

OR (95% CI)

p value

Estimate

OR (95% CI)

p value

rs12979860

 CC

NA

1

 

NA

1

 

 TT

1.095

2.988 (1.208–7.395)

0.018*

1.755

5.783 (1.279–26.142)

0.023*

 TC

0.550

1.732 (0.879–3.415)

0.113

1.127

3.086 (1.247–7.642)

0.015*

rs 8,099,917

 TT

NA

1

 

NA

1

 

 GG

1.007

2.738 (0.886–8.454)

0.080

−0.240

0.787 (0.141–4.375)

0.784

 TG

−0.124

0.883 (0.451–1.730)

0.717

−0.672

0.511 (0.197–1.325)

0.167

Age

0.051

1.052 (1.023–1.082)

<0.001*

0.036

1.037 (1.008–1.067)

0.012*

Gender

−0.516

0.597 (0.312–1.141)

0.118

0.546

1.727 (0.843–3.537)

0.135

  1. Odds ratio were constructed considering favourable genotypes (rs12979860-CC and rs 8,099,917-TT) as reference. OR: Odds ratio; CI: Confidence Interval; *p < 0.05
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Virology Journal

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