Skip to main content

Advertisement

Table 3 Logistic regression of each polymorphism in cases (chronic HCV-infected patients) versus controls (uninfected individuals)

From: IL28B gene polymorphism rs12979860, but not rs8099917, contributes to the occurrence of chronic HCV infection in Uruguayan patients

Factor Univariable Models Multivariable Model
Estimate OR (95% CI) p value Estimate OR (95% CI) p value
rs12979860
 CC NA 1   NA 1  
 TT 1.095 2.988 (1.208–7.395) 0.018* 1.755 5.783 (1.279–26.142) 0.023*
 TC 0.550 1.732 (0.879–3.415) 0.113 1.127 3.086 (1.247–7.642) 0.015*
rs 8,099,917
 TT NA 1   NA 1  
 GG 1.007 2.738 (0.886–8.454) 0.080 −0.240 0.787 (0.141–4.375) 0.784
 TG −0.124 0.883 (0.451–1.730) 0.717 −0.672 0.511 (0.197–1.325) 0.167
Age 0.051 1.052 (1.023–1.082) <0.001* 0.036 1.037 (1.008–1.067) 0.012*
Gender −0.516 0.597 (0.312–1.141) 0.118 0.546 1.727 (0.843–3.537) 0.135
  1. Odds ratio were constructed considering favourable genotypes (rs12979860-CC and rs 8,099,917-TT) as reference. OR: Odds ratio; CI: Confidence Interval; *p < 0.05