TY - JOUR AU - Wigren Byström, Julia AU - Näslund, Jonas AU - Trulsson, Fredrik AU - Evander, Magnus AU - Wesula Lwande, Olivia AU - Ahlm, Clas AU - Bucht, Göran PY - 2018 DA - 2018/01/19 TI - Quantification and kinetics of viral RNA transcripts produced in Orthohantavirus infected cells JO - Virology Journal SP - 18 VL - 15 IS - 1 AB - Rodent borne viruses of the Orthohantavirus genus cause hemorrhagic fever with renal syndrome among people in Eurasia, and hantavirus cardiopulmonary syndrome in the Americas. At present, there are no specific treatments or efficient vaccines against these diseases. Improved understanding of viral transcription and replication may instigate targeted treatment of Orthohantavirus infections. For this purpose, we investigated the kinetics and levels of viral RNA transcription during an ongoing infection in-vitro. SN - 1743-422X UR - https://doi.org/10.1186/s12985-018-0932-8 DO - 10.1186/s12985-018-0932-8 ID - Wigren Byström2018 ER -