Table 2 Pairs of interacting DE miRNAs and predicted target mRNAs (TLR and RLR signalling pathways) in PCMV-infected thymus
miRNAs | miRNA expression level PCMV infected vs. control Log2 (Fold change) | miRNA target Genes | Target mRNA expression level PCMV infected vs. control Log2 (Fold change value) | Target gene related signaling pathways |
|---|---|---|---|---|
miR-10a-5p | +2.53 | TLR6 | −2.88 | Toll-like receptor signaling pathway |
miR-10a-5p | +2.53 | TLR7 | −2.01 | Toll-like receptor signaling pathway |
miR-27b-3p | +4.84 | PIK3CG | −2.77 | Toll-like receptor signaling pathway |
miR-27b-3p | +4.84 | JAK2 | −2.15 | Toll-like receptor signaling pathway |
miR-27b-3p | +4.84 | DHX58 | −4.95 | RIG-I-like receptor signaling pathway |
miR-30a-5p | +3.99 | CXCL9 | −3.93 | Toll-like receptor signaling pathway |
miR-30a-5p | +3.99 | IL12B | −4.2 | Toll-like receptor signaling pathway |
miR-30a-5p | +3.99 | IL12B | −4.2 | RIG-I-like receptor signaling pathway |
miR-30a-5p | +3.99 | MAP3K1 | −3.03 | RIG-I-like receptor signaling pathway |
miR-30a-5p | +3.99 | TANK | −2.09 | RIG-I-like receptor signaling pathway |
miR-143-3p | +6.68 | CD40 | −4.97 | Toll-like receptor signaling pathway |
miR-143-3p | +6.68 | JAK3 | −2.69 | Toll-like receptor signaling pathway |
miR-143-3p | +6.68 | DDX58 | −4.44 | RIG-I-like receptor signaling pathway |
miR-143-3p | +6.68 | IKBKB | −2.16 | RIG-I-like receptor signaling pathway |
miR-148a-3p | +2.46 | MAPK14 | −3.77 | Toll-like receptor signaling pathway |
miR-148a-3p | +2.46 | STAT1 | −2.67 | Toll-like receptor signaling pathway |
miR-148a-3p | +2.46 | STAT5B | −2.55 | Toll-like receptor signaling pathway |
miR-148a-3p | +2.46 | DDX3X | −2.94 | RIG-I-like receptor signaling pathway |
miR-novel-chr2_21624 | +6.68 | IKBKB | −2.16 | Toll-like receptor signaling pathway |
miR-novel-chr2_21624 | +6.68 | MAP3K7 | −3.96 | Toll-like receptor signaling pathway |
miR-novel-chr2_21624 | +6.68 | MAP3K7 | −3.96 | RIG-I-like receptor signaling pathway |
miR-novel-chr2_21624 | +6.68 | MAPK14 | −3.77 | RIG-I-like receptor signaling pathway |