Fig. 4
From: Evaluation of a method to measure HHV-6B infection in vitro based on cell size
Performance of size measurements as a method to differentiate non-infected from infected cells and/or cultures. ROC curves obtained for size of individual cells (a) and for average size of cells (b), using a non-infected culture as control and infected cultures at 4 or 7 dpi as experimental conditions. The AUC and significance level are shown in each case. Non-linear fit for each pair of data analyzed showing the cutoff selected when the analysis was done using size of individual cells (c) or average size of cells (d) at 4 or 7 dpi. The shaded area comprises the range of sizes for infected cells or cultures at the selected cutoffs. e. Estimation of the percentage of infected cells derived from the analysis using size of individual cells. Statistical significance level determined by Mann-Whitney