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Fig. 6 | Virology Journal

Fig. 6

From: Enhanced human enterovirus 71 infection by endocytosis inhibitors reveals multiple entry pathways by enterovirus causing hand-foot-and-mouth diseases

Fig. 6

The effect of CPZ on CV-A16 infection. A549, Hela, RD and HepG2 cells were pretreated with CPZ (20 μM) or DMSO for 2 h. Then the cells were infected by CV-A16 at an MOI of 1. At 12 hpi (A549 and RD) or 24 hpi (HepG2 and Hela), flow cytometry was applied to determine the viral infectivity. The representative percentages of the infected cells were indicated (a). b. The plot showed the summary of three independent experiments. c. Virus titers in A549, RD, HepG2 and Hela cells were measured and shown in TCID50. The data were shown as means ± SD from three independent experiments. *, p < 0.05

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