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Fig. 6 | Virology Journal

Fig. 6

From: The CC chemokine ligand (CCL) 1, upregulated by the viral transactivator Tax, can be downregulated by minocycline: possible implications for long-term treatment of HTLV-1-associated myelopathy/tropical spastic paraparesis

Fig. 6

Minocycline inhibits the production of CCL1 in HTLV-1-infected T-cell lines. Effect of minocycline on CCL1 protein expression in the HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)-derived HTLV-1-infected T-cell line ILT-M1 and in the HTLV-1-transformed cell line C5MJ. Minocycline suppressed the expression of CCL1 in both ILT-M1 and C5MJ cell lines in a dose-dependent manner

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