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Fig. 5 | Virology Journal

Fig. 5

From: The CC chemokine ligand (CCL) 1, upregulated by the viral transactivator Tax, can be downregulated by minocycline: possible implications for long-term treatment of HTLV-1-associated myelopathy/tropical spastic paraparesis

Fig. 5

Plasma levels of CCL1 were significantly higher in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) than in HTLV-1-seronegative patients with multiple sclerosis (MS) and asymptomatic HTLV-1 healthy carriers (HC). The plasma levels of CCL1 in 31 patients with HAM/TSP, 13 HTLV-1-seronegative patients with MS, 19 HCs, and 10 normal controls (NCs) were examined by ELISA. As shown, the plasma levels of CCL1 were significantly higher in patients with HAM/TSP (mean ± SD: 79.3 ± 30.5 pg/ml) than in HTLV-1-seronegative patients with MS (36.8 ± 11.3 pg/ml), HCs (28.7 ± 2.5 pg/ml), and NCs (28.4 ± 3.2 pg/ml)

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