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Table 1 Demographic and clinical characteristics in subjects

From: The relationship between human leukocyte antigen-DP/DQ gene polymorphisms and the outcomes of HCV infection in a Chinese population

Variables Group A (%) Group B (%) Group C (%) P
  n = 370 n = 194 n = 973  
Mean age, year (SD) 46.86 ± 13.05 47.03 ± 11.26 48.43 ± 13.73 0.090a
Age ≥ 50 (%) 157 (22.6) 74 (10.7) 463 (66.7) 0.026b
Gender     0.860b
 Male 204 (55.1) 110 (56.7) 531 (54.6)  
 Female 166 (44.9) 84 (43.3) 442 (45.4)  
ALT ≥40 U/L 104 (28.1) 27 (13.9) 48 (4.9) <0.001c
AST ≥ 40 U/L 128 (34.6) 30 (15.5) 80 (8.2) <0.001c
High-risk population     <0.001b
 Drug user 155 (41.9) 36 (18.6) 246 (25.3)  
 HD 74 (20.0) 89 (45.9) 551 (56.6)  
 PBD 141 (38.1) 69 (35.6) 176 (18.1)  
HCV genotypes     <0.001b
 1 236 (63.8) 114 (58.8)  
 Non-1 51 (13.8) 53 (27.3)  
 Mixed 83 (22.4) 27 (13.9)  
  1. Group A: chronic HCV infection; Group B: spontaneous HCV clearance; Group C: non-HCV infection; Non-1: genotype 2, 3 and unknown; Mixed: co-infected with genotype 1/ 2/3
  2. Abbreviations: ALT, alanine transaminase; AST, aspartate transaminase; SD, standard deviation; HD, hemodialysis patient; PBD, paid blood donors
  3. a P value of Welch among three groups, heterogeneity of variance
  4. b P value of χ2-test among three/two groups
  5. c P value of Kruskal-Wallis test or Mann-Whitney U test among three/two groups