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Table 1 Demographic and clinical characteristics in subjects

From: The relationship between human leukocyte antigen-DP/DQ gene polymorphisms and the outcomes of HCV infection in a Chinese population

Variables

Group A (%)

Group B (%)

Group C (%)

P

 

n = 370

n = 194

n = 973

 

Mean age, year (SD)

46.86 ± 13.05

47.03 ± 11.26

48.43 ± 13.73

0.090a

Age ≥ 50 (%)

157 (22.6)

74 (10.7)

463 (66.7)

0.026b

Gender

   

0.860b

 Male

204 (55.1)

110 (56.7)

531 (54.6)

 

 Female

166 (44.9)

84 (43.3)

442 (45.4)

 

ALT ≥40 U/L

104 (28.1)

27 (13.9)

48 (4.9)

<0.001c

AST ≥ 40 U/L

128 (34.6)

30 (15.5)

80 (8.2)

<0.001c

High-risk population

   

<0.001b

 Drug user

155 (41.9)

36 (18.6)

246 (25.3)

 

 HD

74 (20.0)

89 (45.9)

551 (56.6)

 

 PBD

141 (38.1)

69 (35.6)

176 (18.1)

 

HCV genotypes

   

<0.001b

 1

236 (63.8)

114 (58.8)

 

 Non-1

51 (13.8)

53 (27.3)

 

 Mixed

83 (22.4)

27 (13.9)

 
  1. Group A: chronic HCV infection; Group B: spontaneous HCV clearance; Group C: non-HCV infection; Non-1: genotype 2, 3 and unknown; Mixed: co-infected with genotype 1/ 2/3
  2. Abbreviations: ALT, alanine transaminase; AST, aspartate transaminase; SD, standard deviation; HD, hemodialysis patient; PBD, paid blood donors
  3. a P value of Welch among three groups, heterogeneity of variance
  4. b P value of χ2-test among three/two groups
  5. c P value of Kruskal-Wallis test or Mann-Whitney U test among three/two groups