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Fig. 4 | Virology Journal

Fig. 4

From: Geraniin extracted from the rind of Nephelium lappaceum binds to dengue virus type-2 envelope protein and inhibits early stage of virus replication

Fig. 4

Effect of geraniin on the penetration of DENV-2 into Vero cells. Vero monolayer was pre-chilled at 4 °C for 1 h and then infected with DENV-2 at 4 °C for another 3 h. After 3 h incubation, geraniin was added. At 10 min interval, extracellular virus was killed by PBS at pH 3. PBS at pH 11 was then added to neutralize acidic PBS. The graph of percentage of DENV-2 plaque inhibition was plotted against time taken for penetration. Data represent mean values ±SEM

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