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Table 2 Overall frequency (%) of minor INSTI resistance mutations and INSTI-selected mutations

From: Molecular evolution of HIV-1 integrase during the 20 years prior to the first approval of integrase inhibitors

 

Overall frequency (%) of

Variant

minor INSTI resistance mutation

INSTI-selected mutation

M50I

 

12.8

V54I

0.9

 

G59E

 

2.1

L68V

1.2

 

L74I

2.7

 

L74 M

0.6

 

L101I

 

36.8

S119R

3.0

 

T122I

 

24.3

T124A

25.8

 

T124 N

  

T125A

 

17.8

A128T

0.9

 

E138D

 

1.5

V151A

0.3

 

V151I

7.4

 

M154I

 

18.4

K156 N

5.3

 

E157Q

2.4

 

G163E

 

2.4

G163R

0.3

 

V165I

  

H171Q

  

G193E

 

10.1

V201I

 

36.8

I203M

 

3.3

T206S

6.8

 

N222 K

  

S230G

0.6

 

S230 N

8.0

 

V260I

0.3