Fig. 6
Distribution of vd-siRNA reads along the CDVd genome. vd-siRNA profile generated from sRNA reads depicted as heat maps showing the reads that mapped onto the positive (+) or negative (−) strand of CDVd. A vd-siRNA hotspot was formed on the negative-strand of the viroid, overlapping the central and variable regions. C, central domain; P, pathogenic domain; TCR, terminal conserved region; CCR, central conserved region; TL, terminal left domain; TR, terminal right domain; V, variable domain