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Fig. 2 | Virology Journal

Fig. 2

From: Chronic hepatitis B carriers with acute on chronic liver failure show increased HBV surface gene mutations, including immune escape variants

Fig. 2

The median incidence of A1762T/G1764A dual mutations in HBV basal core promoter (BCP) region and G1896A mutation in HBV precore (PC) region among different groups (ACLF-CHB, immune active & HBeAg negative hepatitis CHB groups). a The incidence of A1762T/G1764A dual mutations was significantly higher in HBeAg negative hepatitis group than in both HBeAg positive (****p < 0.0001) and HBeAg negative ACLF-CHB groups (****p < 0.0001) and immune active group (*p < 0.05). The dual mutations were also more frequently seen in immune active group than in both ACLF-CHB group (*p < 0.05). b The incidence of G1896A mutation in HBV PC region was significantly more frequent in HBeAg negative hepatitis group than in both ACLF-CHB groups (****p < 0.0001) and immune active group (****p < 0.0001)

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Virology Journal

ISSN: 1743-422X