Fig. 3

Alignment of amino acid sequences of the LHDAg depicting the genotypic, functional and immune epitope domains of the 19 C-terminal amino acids (196–214) of the clathrin heavy chain (CHC) interacting domain bearing a clathrin box-binding (CBD) domain (aa 199–203), a serine at aa 202, isoprenylation (Py) sites at 211–214. The figure shows phosphorylation sites (Pi) (aa 2, 123, 177), acetylation site (Ac) (aa 72), HDV RNA binding domain (RBD) (aa 79–107) and arginine-rich motifs (ARMs) (aa 137–144) of the sHDAg. Refrence sequence for alignment was made with Ethiopian HDV isolate (accession number: HDU81989)