Fig. 2
From: Membrane-anchored CCL20 augments HIV Env-specific mucosal immune responses
Systemic and mucosal Ab responses against HIV-gp120. The mice were immunized with Gag VLPs, standard VLPs(Gag/Env), chimeric VLPs (Gag/Env/ccl20) and standard VLPs mixed with soluble CCL20 (Gag/Env-ccl20) by different immunization routes. The sera and vaginal wash samples were collected 2 weeks after each immunization and final samples were tested in the present study. a, Serum IgG titers; b and c, IgG and IgA titers of vaginal wash, respectively. Assays were performed as described in materials and methods. Results are expressed as means ± standard deviations. P values of less than 0.05 (p < 0.05) were considered to be statistically significant. *, p < 0.05