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Fig. 8 | Virology Journal

Fig. 8

From: A novel bladder cancer - specific oncolytic adenovirus by CD46 and its effect combined with cisplatin against cancer cells of CAR negative expression

Fig. 8

The effects of Ad5/F11p combined with cisplatin on bladder cancer cells. The interaction effects of Ad5/F11p-PSCAE-UPII-E1A (10 MOI) combined with cisplatin (1 μg/ml) at different time points (24, 48, and 72 h after the combined effects) were assessed by CCK-8 assay. The mean of three independent experiments with standard deviation were used to express the data results. The cytotoxic effects of Ad5/F11p-PSCAE-UPII-E1A alon and the interaction effects of Ad5/F11p-PSCAE-UPII-E1A combined with cisplatin were compared on 5637, EJ, and T24 cells (*p < 0.05 means statistically difference, and **p < 0.01 means statistically significant difference)

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