Table 3 Genotype and allele frequencies of rs148314165 and rs200820567 polymorphisms in patients with different clinical liver diseases of chronic HBV infection
Polymorphisms | Chronic hepatitis (n = 165) | Cirrhosis (n = 158) | HCC (n = 96) | P | Chronic hepatitis vs. Cirrhosis | Chronic hepatitis vs. HCC | Cirrhosis vs. HCC | |||
|---|---|---|---|---|---|---|---|---|---|---|
P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | |||||
rs148314165 | ||||||||||
Genotype | 0.846 | 0.865 | 1.057 (0.559–1.997) | 0.566 | 1.252 (0.581–2.695) | 0.670 | 1.184 (0.544–2.579) | |||
TT | 142 (86.1) | 137 (86.7) | 85 (88.5) | |||||||
Tdel | 23 (13.9) | 21 (13.3) | 11 (11.5) | |||||||
Allele | 0.856 | 0.870 | 1.052 (0.570–1.942) | 0.580 | 1.233 (0.587–2.588) | 0.680 | 1.171 (0.552–2.486) | |||
T | 307 (93.0) | 295 (93.4) | 181 (94.3) | |||||||
del | 23 (7.0) | 21 (6.6) | 11 (5.7) | |||||||
rs200820567 | ||||||||||
Genotype | 0.846 | 0.865 | 1.057 (0.559–1.997) | 0.566 | 1.252 (0.581–2.695) | 0.670 | 1.184 (0.544–2.579) | |||
TT | 142 (86.1) | 137 (86.7) | 85 (88.5) | |||||||
TA | 23 (13.9) | 21 (13.3) | 11 (11.5) | |||||||
Allele | 0.856 | 0.870 | 1.052 (0.570–1.942) | 0.580 | 1.233 (0.587–2.588) | 0.680 | 1.171 (0.552–2.486) | |||
T | 307 (93.0) | 295 (93.4) | 181 (94.3) | |||||||
A | 23 (7.0) | 21 (6.6) | 11 (5.7) | |||||||