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Fig. 6 | Virology Journal

Fig. 6

From: Expression pattern of CD11c on lung immune cells after disseminated murine cytomegalovirus infection

Fig. 6

Distinct expression patterns of CD11c and B220 on NK cells of BALB/c and C57BL/6 mice. Control and MCMV groups of BALB/c and C57BL/6 mice were generated as described above. Lung and spleen samples were harvested and NK cells analyzed at 1, 3, 5 and 7 days post infection (dpi). a Lung NK cells from each group at different dpi are shown based on their expression of B220 and CD11c. B220CD11c and B220CD11cint NK cells are the major NK cells in lungs of BALB/c and C57BL/6 mice, respectively. After MCMV infection, the proportions of B220CD11cint in BALB/c mice and B220+CD11cint in C57BL/6 mice were significantly increased, with both peaking at 3 dpi. An obviously higher proportion of B220+CD11cint was observed in C57BL/6 mice. b Spleen NK cells from each group at different dpi are shown based on their expression of B220 and CD11c. B220+CD11c is one of the major constituents of spleen NK cells, without obvious change after MCMV infection, the proportion of which was much higher than that in lung

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