Fig. 6

Distinct expression patterns of CD11c and B220 on NK cells of BALB/c and C57BL/6 mice. Control and MCMV groups of BALB/c and C57BL/6 mice were generated as described above. Lung and spleen samples were harvested and NK cells analyzed at 1, 3, 5 and 7 days post infection (dpi). a Lung NK cells from each group at different dpi are shown based on their expression of B220 and CD11c. B220⁻CD11c⁻ and B220⁻CD11c^int NK cells are the major NK cells in lungs of BALB/c and C57BL/6 mice, respectively. After MCMV infection, the proportions of B220⁻CD11c^int in BALB/c mice and B220⁺CD11c^int in C57BL/6 mice were significantly increased, with both peaking at 3 dpi. An obviously higher proportion of B220⁺CD11c^int was observed in C57BL/6 mice. b Spleen NK cells from each group at different dpi are shown based on their expression of B220 and CD11c. B220⁺CD11c⁻ is one of the major constituents of spleen NK cells, without obvious change after MCMV infection, the proportion of which was much higher than that in lung