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Fig. 4 | Virology Journal

Fig. 4

From: Comparison of the protective efficacy between single and combination of recombinant adenoviruses expressing complete and truncated glycoprotein, and nucleoprotein of the pathogenic street rabies virus in mice

Fig. 4

Survival rates of mice immunized with Raboral vaccinia-rabies glycoprotein (V-RG®) vaccine and mixed virus (Ad-0910G + Ad-0910 N) by the oral route after RABV CVS-N2c challenge. Mice in the V-RG (1) and Ad-0910G + Ad-0910 N (1) group were inoculated with 0.1 mL of VRG vaccine and mixed virus (Ad-0910G + Ad-0910 N) via the oral route only once. Mice of V-RG (2) and Ad-0910G + Ad-0910 N (2) group were inoculated orally again one week after initial inoculation. Mice in the control group were inoculated with an equal volume of PBS. All mice were challenged with 30 μL of CVS-N2c (25 LD50/0.03 mL) by the intracranial (IC) route 14 days following vaccination. After challenge, the survival of mice was checked daily for 2 weeks

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