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Table 1 Positive and negative predictive value, sensitivity and specificity of NGS-HPV vs Linear Array

From: Genotyping of high-risk anal human papillomavirus (HPV): ion torrent-next generation sequencing vs. linear array

  %PPV (95% CI) %NPV (95% CI) Sensitivity (95% CI) Specificity (95% CI)
HR-HPV 90.0 (79.5–96.2) 93.3 (83.8–98.2) 93.1 (83.3–98.1) 90.3 (80.1–96.4)
LR-HPV 73.3 (54.1–87.7) 92.2 (87.3–95.7) 61.1 (43.5–76.9) 95.4 (91.1–98.0)
All HPV 84.4 (75.2–91.2) 92.5 (88.4–95.4) 80.9 (71.4–88.2) 94.1 (90.2–96.7)
  1. Abbreviations: NGS Next generation sequencing, HR-HPV High risk human papillomavirus, LR-HPV Low-risk human papillomavirus, PPV Positive predictive value, NPV Negative predictive value, CI Confidence intervals