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Table 1 Positive and negative predictive value, sensitivity and specificity of NGS-HPV vs Linear Array

From: Genotyping of high-risk anal human papillomavirus (HPV): ion torrent-next generation sequencing vs. linear array

 

%PPV (95% CI)

%NPV (95% CI)

Sensitivity (95% CI)

Specificity (95% CI)

HR-HPV

90.0 (79.5–96.2)

93.3 (83.8–98.2)

93.1 (83.3–98.1)

90.3 (80.1–96.4)

LR-HPV

73.3 (54.1–87.7)

92.2 (87.3–95.7)

61.1 (43.5–76.9)

95.4 (91.1–98.0)

All HPV

84.4 (75.2–91.2)

92.5 (88.4–95.4)

80.9 (71.4–88.2)

94.1 (90.2–96.7)

  1. Abbreviations: NGS Next generation sequencing, HR-HPV High risk human papillomavirus, LR-HPV Low-risk human papillomavirus, PPV Positive predictive value, NPV Negative predictive value, CI Confidence intervals