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Fig. 2 | Virology Journal

Fig. 2

From: Cross-border spread, lineage displacement and evolutionary rate estimation of rabies virus in Yunnan Province, China

Fig. 2

Molecular clock phylogeographic analysis of Southeast Asian RABVs using the N gene. Panel a: Maximum clade credibility trees of the RABV SEA clades in Asia. Branches are colored by geographic region as inferred by Bayesian phylogeographic methods and the horizontal branches are drawn on a timescale of years. The correspondance between colors and locations is as in the legend. Black and grey arrows indicate independent introduction events of RABV into Yunnan. The grey arrows mark single Yunnan lineages while the black arrows point to Yunnan clusters. Numbers next to the names of the well-supported Yunnan cluster indicate the posterior root node support for that cluster. The low posterior support for the branching structure that makes the YN-B clade an ingroup of SEA lineages in the MCC tree is given next to the corresonding node. Panel b Violin plot representation of the tMRCA’s 95%HPD estimates of the five Yunnan clusters. The dashed line marks the start of the most recent RABV epidemic in Yunnan. Panel c Enlargement of the SEA-3 clade. The dashed grey line marks the onset of the most recent RABV epidemic in Yunnan, which started in 2000. The median estimate of the YN-B tMRCA is given next to the black arrow that points to the YN-B root node. The origin of >99% of all strains entering Yunnan can be traced to north and south China. Note that the rate decline in the most recent years reflects the loss of branches in the sampling time period, rather than the start of an actual tendency

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