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Table 2 FMDV-Mut tissue distribution

From: Pathogenesis of virulent and attenuated foot-and-mouth disease virus in cattle

Time point (hpi) 24 48 72
Animal ID 699 9106 9107 1003 1024 1035
Clinical score 0 0 0 0 0 0
FMDV RNA copies/μl in serum neg neg neg neg neg neg
Tissue sample       
Oral cavity/oropharynx
 Anterior tongue - - - - - -
 Lingual tonsil - - - - 3.15 -
 Anterior hard palate NA - - - - -
 Palatine tonsil NA - - - 3.14 -
 Ventral soft palate-Caudal - - - - 3.87 -
Nasal cavity/Nasopharynx
 Nasal turbinates-posterior - - - - - -
 Dorsal soft palate -Rostral + 2.85 3.16 - 3.73 -
 Dorsal soft palate -Caudal 2.68 4.74 4.15 2.83 4.38 2.95
 Dorsal nasopharynx -Rostral 4.43 - - - 3.01 3.07
 Dorsal nasopharynx -Caudal + 2.57 4.54 - 3.42 3.05
 Nasopharyngeal tonsil - - - + - -
 Ventral epiglottis - - 4.31 - 4.10 -
 Larynx 2.70 - 2.75 5.12 3.10 -
Lungs/Trachea
 Trachea −10 cm - - - -   -
 Proximal cranial lobe NA - 3.47 4.09 4.79 2.96
 Mid cranial lobe NA - 3.86 3.13 2.68 3.91
 Distal cranial lobe 3.36 2.57 + 3.00 4.26 3.98
 Proximal mid lobe NA - 3.95 3.22 5.55 3.90
 Mid mid lobe NA - 5.56 3.52 4.25 3.92
 Distal mid lobe 3.78 - 3.47 - 3.54 3.22
 Proximal caudal lobe NA - 4.99 4.08 4.75 3.73
 Mid caudal lobe NA 3.49 - 3.40 4.27 -
 Distal caudal lobe 3.62 3.04 3.43 - 3.31 -
Additional tissues
 Interdigital cleft NA - - - - -
 Medial Retropharyngeal LN NA - - - + -
 Submandibular LN NA - - - 2.57 -
 Hilar LN NA - - - 2.98 -
  1. Tabulated Numbers indicate FMDV RNA genome copy numbers (GCN) per mg of tissue
  2. Bold and underlined text indicates infectious virus isolated
  3. ‘+’ indicates infectious virus isolated without concurrent detection of FMDV genome
  4. ‘-’ indicates negative for detection of FMDV RNA and infectious virus