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Table 1 Comparison of agreement for HPV detection in urine versus cells, for E7-MPG and GP5+/6+ tests

From: Evaluation of the performance of Human Papillomavirus testing in paired urine and clinician-collected cervical samples among women aged over 30 years in Bhutan

  

HPV result (n)

urine/cells

Urine positivity

Cells positivity

Urine:cells

Prevalence ratio

McNemar

p-value

HPV detection in urine, versus cells as gold standard

+/+

-/-

+/-

-/+

Sensitivity

Specificity

21 HPV types

E7-MPG

41

23

15

10

62.9%

57.3%

1.10

0.32

80 (67–90)

61 (43–76)

GP5+/6+RLB

21

47

6

15

30.3%

40.4%

0.75

0.05

58 (41–75)

89 (77–96)

     

2.08*

1.42*

    

HPV6/11/16/18

E7-MPG

18

63

5

3

25.8%

23.6%

1.09

0.48

86 (64–97)

93 (84–98)

GP5+/6+RLB

11

67

3

8

15.7%

21.3%

0.74

0.14

58 (33–80)

96 (88–99)

     

1.64*

1.11*

    
  1. HPV human papillomavirus *E7-MPG:GP5+/6+RLB ratio