Fig. 5

Effect of miR-17-5p and miR-1281 mimics on FMDV infection in cell culture. a Cells were transfected with miR-17-5p mimics in parallel with negative controls: untransfected and irrelevant miR-342-5p. Forty-eight hours post-transfection, the cells were infected with FMDV A24 Cruzeiro. Subsequent to infection, the resulting samples were evaluated for virus titers, which are plotted. b Cells were transfected with miR-1281 mimics following the same procedure as miR-17-5p (a). Resulting virus titers are plotted as shown. Both panels a and b are representative of two independent experiments that were performed in duplicate. miR-17-5p was included in the second experimental set in panel b to confirm the non-effect seen in panel a