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Table 3 Responses between different rtA181T/sW172 mutations

From: Antiviral efficacy of entecavir for hepatitis B virus rtA181V/T mutants

Characteristics rtA181T/sW172* mutation group (n = 22) other missense mutations group (n = 4) P value
Before Rescue
HBV DNA (log10 IU/mL)
 Mean ± SD 4.16 ± 2.35 3.61 ± 0.21 0.298
HBsAg (lg IU/ml)
 Mean ± SD 3.52 ± 0.48 3.46 ± 0.40 0.795
ALT (U/L)
 Mean ± SD 142.5 ± 253.8 59.0 ± 40.9 0.524
After Rescue
HBV DNA Reduction (log10 IU/mL)
 6th Month (Mean ± SD) 3.31 ± 2.25 3.61 ± 0.21 0.797
 12th Month (Mean ± SD) 3.66 ± 2.18 3.61 ± 0.21 0.918
HBsAg (log10 IU/ml)
 6th Month (Mean ± SD) 3.50 ± 0.45 3.47 ± 0.42 0.908
 12th Month (Mean ± SD) 3.31 ± 0.50 3.14 ± 0.50 0.529
ALT (U/L)
 6th Month (Mean ± SD) 39.6 ± 19.3 20.5 ± 11.7 0.069
 12th Month (Mean ± SD) 39.0 ± 20.0 23.5 ± 3.1 0.142