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Table 2 Relationship between TLR2, TLR4 and TLR9 SNPs and the occurrence of HCMV infection among pregnant women

From: Toll-like receptors genes polymorphisms and the occurrence of HCMV infection among pregnant women

Gene polymorphism Genetic model Genotype Genotype prevalence rates; n (%) a ORb (95% CI) c P-valued
Infected cases Uninfected controls
TLR2 2258 G > A - GG 62 (93.9%) 59 (92.2%) 1.00  
GA 4 (6.1%) 5 (7.8%) 0.76 (0.19–2.97) 0.690
TLR4 896 A > G - AA 56 (91.8%) 53 (86.9%) 1.00  
AG 5 (8.2%) 8 (13.1%) 0.59 (0.18–1.92) 0.380
TLR4 1196 C > T - CC 60 (90.9%) 55 (87.3%) 1.00  
CT 6 (9.1%) 8 (12.7%) 0.69 (0.22–2.11) 0.510
TLR9 2848 G > A Codominant GG 8 (13.3%) 13 (20.3%) 0.39 (0.13–1.13) 0.093
GA 25 (41.7%) 34 (53.1%) 0.46 (0.21–1.03)
AA 27 (45.0%) 17 (26.6%) 1.00
Dominant AA 27 (45.0%) 17 (26.6%) 1.00  
GA-GG 33 (55.0%) 47 (73.4%) 0.44 (0.21–0.94) 0.032
Recessive AA-GA 52 (86.7%) 51 (79.7%) 1.00  
GG 8 (13.3%) 13 (20.3%) 0.60 (0.23–1.58) 0.300
Overdominant GG-AA 35 (58.3%) 30 (46.9%) 1.00  
GA 25 (41.7%) 34 (53.1%) 0.63 (0.31–1.28) 0.200
  1. a n, number of tested pregnant women
  2. b OR, odds ratio
  3. c 95% CI, confidence interval
  4. d logistic regression model; P ≤ 0.050 is considered as significant