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Table 4 Inhibitory activity of N30 against different strains of Human enterovirus 71

From: A novel benzo-heterocyclic amine derivative N30 inhibits influenza virus replication by depression of Inosine-5’-Monophospate Dehydrogenase activity

Strain N30 Pirodavir
TC50 (μM) IC50 (μM) SI TC50 (μM) IC50 (μM) SI
EV71(SZ98) 89.56 ± 4.25 10.63 ± 3.76 8.42 32.57 ± 0.55 0.27 ± 0.27 120.6
EV71(BrCr) 89.56 ± 4.25 8.04 ± 3.77 11.14 32.57 ± 0.55 0.16 ± 0.00 203.56