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Table 4 Inhibitory activity of N30 against different strains of Human enterovirus 71

From: A novel benzo-heterocyclic amine derivative N30 inhibits influenza virus replication by depression of Inosine-5’-Monophospate Dehydrogenase activity

Strain

N30

Pirodavir

TC50 (μM)

IC50 (μM)

SI

TC50 (μM)

IC50 (μM)

SI

EV71(SZ98)

89.56 ± 4.25

10.63 ± 3.76

8.42

32.57 ± 0.55

0.27 ± 0.27

120.6

EV71(BrCr)

89.56 ± 4.25

8.04 ± 3.77

11.14

32.57 ± 0.55

0.16 ± 0.00

203.56

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Virology Journal

ISSN: 1743-422X