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Table 3 Inhibitory activity of N30 against different strains of Cosackie B virus

From: A novel benzo-heterocyclic amine derivative N30 inhibits influenza virus replication by depression of Inosine-5’-Monophospate Dehydrogenase activity

Strain N30 RBV
TC50 (μM) IC50 (μM) SI TC50 (mM) IC50 (mM) SI
CVB1 89.56 ± 4.25 6.28 ± 1.61 14.26 >20.00 2.37 ± 0.36 >8.44
CVB2 89.56 ± 4.25 11.65 ± 2.94 7.69 >20.00 2.27 ± 0.18 >8.81
CVB3 89.56 ± 4.25 1.82 ± 2.76 49.21 >20.00 3.13 ± 1.21 >6.39
CVB4 89.56 ± 4.25 10.37 ± 3.13 8.64 >20.00 2.47 ± 1.60 >8.10
CVB5 89.56 ± 4.25 2.54 ± 1.43 35.26 >20.00 1.20 ± 0.53 >16.67
CVB6 89.56 ± 4.25 6.81 ± 1.89 13.15 >20.00 4.56 ± 2.41 >4.39