Table 2 Inhibitory activity of N30 against eight influenza strains
Strain | N30 | RBV | OC | AH | ||||
|---|---|---|---|---|---|---|---|---|
IC50(μM) | SI | IC50(μM) | SI | IC50(μM) | SI | IC50(μM) | SI | |
A/FortMonmouth/1/1947 | 1.93 ± 0.16 | 34.54 | 1.64 ± 0.72 | >121.95 | 0.25 ± 0.01 | >200 | 0.65 ± 0.59 | >307.69 |
A/tianjinjinnan/15/2009 | 1.67 ± 0.49 | 39.92 | 2.54 ± 1.25 | >78.74 | 2.57 ± 0.10 | >19.45 | 18.24 ± 0.24 | >10.96 |
A/liaoningzhenxing/1109/2010 | 3.43 ± 3.36 | 19.44 | 4.92 ± 3.02 | >40.65 | 3.20 ± 0.21 | >15.58 | 10.13 ± 0.04 | >19.74 |
A/wuhan/359/1995 | 1.31 ± 0.87 | 50.89 | 8.23 ± 6.31 | >24.30 | 0.12 ± 0.01 | >416.67 | 15.64 ± 0.31 | >12.78 |
A/fujiantongan/196/2009 | 1.13 ± 0.43 | 59.00 | 4.42 ± 0.74 | >45.25 | 0.28 ± 0.01 | >178.57 | 78.84 ± 3.04 | >2.54 |
A/hunanzhuhui/1222/2010 | 1.76 ± 0.24 | 37.89 | 2.34 ± 0.98 | >85.47 | 0.78 ± 0.02 | >64.10 | 57.24 ± 2.23 | >3.49 |
BV/shenzhen/155/2005 | 1.16 ± 0.69 | 57.47 | 1.70 ± 0.57 | >117.65 | 1.02 ± 0.08 | >49.02 | >200 | - |
BY/fujianxinluo/54/2006 | 0.70 ± 0.18 | 95.24 | 2.48 ± 0.53 | >80.65 | 0.56 ± 0.02 | >89.28 | >200 | - |