|
Strain
|
N30
|
RBV
|
OC
|
AH
|
|---|
|
IC50(μM)
|
SI
|
IC50(μM)
|
SI
|
IC50(μM)
|
SI
|
IC50(μM)
|
SI
|
|---|
|
A/FortMonmouth/1/1947
|
1.93 ± 0.16
|
34.54
|
1.64 ± 0.72
|
>121.95
|
0.25 ± 0.01
|
>200
|
0.65 ± 0.59
|
>307.69
|
|
A/tianjinjinnan/15/2009
|
1.67 ± 0.49
|
39.92
|
2.54 ± 1.25
|
>78.74
|
2.57 ± 0.10
|
>19.45
|
18.24 ± 0.24
|
>10.96
|
|
A/liaoningzhenxing/1109/2010
|
3.43 ± 3.36
|
19.44
|
4.92 ± 3.02
|
>40.65
|
3.20 ± 0.21
|
>15.58
|
10.13 ± 0.04
|
>19.74
|
|
A/wuhan/359/1995
|
1.31 ± 0.87
|
50.89
|
8.23 ± 6.31
|
>24.30
|
0.12 ± 0.01
|
>416.67
|
15.64 ± 0.31
|
>12.78
|
|
A/fujiantongan/196/2009
|
1.13 ± 0.43
|
59.00
|
4.42 ± 0.74
|
>45.25
|
0.28 ± 0.01
|
>178.57
|
78.84 ± 3.04
|
>2.54
|
|
A/hunanzhuhui/1222/2010
|
1.76 ± 0.24
|
37.89
|
2.34 ± 0.98
|
>85.47
|
0.78 ± 0.02
|
>64.10
|
57.24 ± 2.23
|
>3.49
|
|
BV/shenzhen/155/2005
|
1.16 ± 0.69
|
57.47
|
1.70 ± 0.57
|
>117.65
|
1.02 ± 0.08
|
>49.02
|
>200
|
-
|
|
BY/fujianxinluo/54/2006
|
0.70 ± 0.18
|
95.24
|
2.48 ± 0.53
|
>80.65
|
0.56 ± 0.02
|
>89.28
|
>200
|
-
|
- Note: The TC50 of N30, OC, RBV and Amantadine were 66.67 μM, >50 μM, >200 μM, >200 μM, respectively
- “−”: no antiviral activity at the maximal nontoxic concentration
