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Fig. 3 | Virology Journal

Fig. 3

From: A novel benzo-heterocyclic amine derivative N30 inhibits influenza virus replication by depression of Inosine-5’-Monophospate Dehydrogenase activity

Fig. 3

N30 does not inhibit the protein expression but inhibit the enzymatic reaction of IMPDH. a The effect of N30 on IMPDH type II expression. MDCK cells were treated with RBV, OC or serial dilutions of N30 for 24 h before intracellular protein extraction. The protein expression of IMPDH was detected by western blot. b The effect of N30 on IMPDH type II activity. The experiments were performed in triplicate, and each value represents mean ± SD

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