Fig. 3From: A novel benzo-heterocyclic amine derivative N30 inhibits influenza virus replication by depression of Inosine-5’-Monophospate Dehydrogenase activityN30 does not inhibit the protein expression but inhibit the enzymatic reaction of IMPDH. a The effect of N30 on IMPDH type II expression. MDCK cells were treated with RBV, OC or serial dilutions of N30 for 24 h before intracellular protein extraction. The protein expression of IMPDH was detected by western blot. b The effect of N30 on IMPDH type II activity. The experiments were performed in triplicate, and each value represents mean ± SDBack to article page