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Table 3 Representative DEGs involved in host defenses at different time points

From: Transcriptional profiling of host cell responses to encephalomyocarditis virus (EMCV)

Mock VS 12 hpi

Mock VS 24 hpi

Mock VS 30 hpi

Gene ID (Symbol)

Fold

Gene ID (Symbol)

Fold

Gene ID (Symbol)

Fold

101825392 (CD38)

−2.63

101824408 (NLRP3)

−3.57

101823322 (TRAF2)

2.57

101832339 (LGP2)

−2.04

101838586 (TAK1)

2.16

101824715 (TNFRSF25)

−84.75

101838791 (AP1)

2.26

101842900 (C3)

2.00

101842545 (ID3)

2.36

101842545 (ID3)

−1.96

101835832 (DCN)

67.01

101842900 (C3)

3.19

101843869 (MX2)

−2.00

101834866 (A20)

1.82

101834778 (ZFP36)

5.88

101836016 (IL18)

−1.64

101827190 (IRF7)

−1.67

101823908 (PTGS2, COX2)

4.53

101834265 (PKA)

1.67

101838791 (AP1)

1.77

101838586 (TAK1)

2.98

101834866 (A20)

−1.82

101837879 (CARD6)

1.61

101835832 (DCN)

120.55

101834601 (TGFB1)

1.62

101830419 (PI3KI)

2.45

101834866 (A20)

2.30

    

101832093 (ATG12)

2.47

101830419 (PI3KI)

3.15

KEGG pathways:

RIG-I-like receptor signaling pathway: LGP2, TAK1, IRF7, TRAF2, ATG12

Apoptosis: PKA, TRAF2

Epstein-Barr virus infection: CD38, AP1, TAK1, A20, TRAF2

TGF-beta signaling pathway: ID3, DCN, TGFB1

Influenza A: MX2, IL18, NLRP3, IRF7, AP1

NF-kappa B signaling pathway: A20, TAK1, TRAF2, PTGS2

Herpes simplex infection: C3, IRF7, TRAF2, TAK1

Cytokine-cytokine receptor interaction: TNFRSF25, IL18

HTLV-I infection: ZFP36

Complement and coagulation cascades: PI3KI, C3

NOD-like receptor signaling pathway: CARD6, TAK1, NLRP3, A20

  1. P < 0.05