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Table 6 Relation between demographic, clinical, and biochemical findings and CMV and/or EBV as detected in leukocytes by qualitative PCR assay in leukemic patients

From: Epstein-Barr virus and cytomegalovirus infections and their clinical relevance in Egyptian leukemic pediatric patients

  EBV alone
n = 14
CMV alone
n = 10
Both positive
n = 9
Both negative
n = 17
p value
Age      0.45
 ≤6 years (n = 23) 8 (34.8%) 6 (26.1%) 3 (13%) 6 (26.1%)
 >6 years (n = 27) 6 (22.2%) 4 (14.8%) 6 (22.2%) 11 (40.7%)
Sex      0.94
 Male (n = 26) 7 (26.9%) 6 (23.1%) 5 (19.2%) 8 (30.8%)
 Female (n = 24) 7 (29.2%) 4 (16.7%) 4 (16.7%) 9 (37.5%)
Mucositis      0.60
 Yes (n = 22) 4 (18.2%) 5 (22.7%) 5 (22.7%) 8 (36.4%)
 No (n = 28) 10 (35.7%) 5 (17.9%) 4 (14.3%) 9 (32.1%)
Organomegaly      0.61
 Yes (n = 35) 11 (31.4%) 8 (22.9%) 6 (17.1%) 10 (28.6%)
 No (n = 15) 3 (20.0%)) 2 (13.3%) 3 (20.0%) 7 (46.7%)
DFN (days)      0.79
 <26.5 (n = 25) 7 (28.0%) 4 (16.0%) 4 (16.0%) 10 (40.0%)
 >26.5 (n = 25) 7 (28.0%) 6 (24.0%) 5 (20.0%) 7 (28.0%)
ANC(×109/L)      0.84
 <0.13 (n = 25) 8 (32%) 4 (16%) 5 (20%) 8 (32%)
 ≥0.13 (n = 25) 6 (24%) 6 (24%) 4 (16%) 9 (36%)
Plt count(×109/L)      0.90
 <39.5 (n = 25) 7 (28.0%) 6 (24.0%) 4 (16.0%) 8 (32.0%)
 ≥39.5 (n = 25) 7 (28.0%) 4 (16.0%) 5 (20.0%) 9 (36.0%)
Hb(gm/dL)      0.12
 <7.4 (n = 25) 8 (32%) 5 (20%) 7 (28%) 5 (20%)
 ≥7.4 (n = 25) 6 (24.0%) 5 (20.0%) 2 (8.0%) 12 (48.0%)
AMC(×109/L)      0.67
 <0.11 (n = 25) 8 (32%) 6 (24%) 3 (12%) 8 (32%)
 ≥0.11 (n = 25) 6 (24%) 4 (16%) 6 (24%) 9 (36%)
TLC(cell/mm3)      0.59
 <11950 (n = 25) 6 (24%) 6 (24%) 6 (24%) 7 (28%)
 ≥11950 (n = 25) 8 (32%) 4 (16%) 3 (12%) 10 (40%)
ALC(×109/L)      0.79
 <1.2 (n = 24) 8 (33.3%) 4 (16.7%) 5 (20.8%) 7 (29.2%)
 ≥1.2 (n = 26) 6 (23.1%) 6 (23.1%) 4 (15.4%) 10 (38.5%)
  1. DFN Duration of febrile neutropenia, HG hemoglobin, TLC Total leukocytic count, Plt platelets, ANC Absolute neutrophilic count, AMC Absolute monocytic count, ALC Absolute lymphocytic count