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Table 6 Relation between demographic, clinical, and biochemical findings and CMV and/or EBV as detected in leukocytes by qualitative PCR assay in leukemic patients

From: Epstein-Barr virus and cytomegalovirus infections and their clinical relevance in Egyptian leukemic pediatric patients

 

EBV alone

n = 14

CMV alone

n = 10

Both positive

n = 9

Both negative

n = 17

p value

Age

    

0.45

 ≤6 years (n = 23)

8 (34.8%)

6 (26.1%)

3 (13%)

6 (26.1%)

 >6 years (n = 27)

6 (22.2%)

4 (14.8%)

6 (22.2%)

11 (40.7%)

Sex

    

0.94

 Male (n = 26)

7 (26.9%)

6 (23.1%)

5 (19.2%)

8 (30.8%)

 Female (n = 24)

7 (29.2%)

4 (16.7%)

4 (16.7%)

9 (37.5%)

Mucositis

    

0.60

 Yes (n = 22)

4 (18.2%)

5 (22.7%)

5 (22.7%)

8 (36.4%)

 No (n = 28)

10 (35.7%)

5 (17.9%)

4 (14.3%)

9 (32.1%)

Organomegaly

    

0.61

 Yes (n = 35)

11 (31.4%)

8 (22.9%)

6 (17.1%)

10 (28.6%)

 No (n = 15)

3 (20.0%))

2 (13.3%)

3 (20.0%)

7 (46.7%)

DFN (days)

    

0.79

 <26.5 (n = 25)

7 (28.0%)

4 (16.0%)

4 (16.0%)

10 (40.0%)

 >26.5 (n = 25)

7 (28.0%)

6 (24.0%)

5 (20.0%)

7 (28.0%)

ANC(×109/L)

    

0.84

 <0.13 (n = 25)

8 (32%)

4 (16%)

5 (20%)

8 (32%)

 ≥0.13 (n = 25)

6 (24%)

6 (24%)

4 (16%)

9 (36%)

Plt count(×109/L)

    

0.90

 <39.5 (n = 25)

7 (28.0%)

6 (24.0%)

4 (16.0%)

8 (32.0%)

 ≥39.5 (n = 25)

7 (28.0%)

4 (16.0%)

5 (20.0%)

9 (36.0%)

Hb(gm/dL)

    

0.12

 <7.4 (n = 25)

8 (32%)

5 (20%)

7 (28%)

5 (20%)

 ≥7.4 (n = 25)

6 (24.0%)

5 (20.0%)

2 (8.0%)

12 (48.0%)

AMC(×109/L)

    

0.67

 <0.11 (n = 25)

8 (32%)

6 (24%)

3 (12%)

8 (32%)

 ≥0.11 (n = 25)

6 (24%)

4 (16%)

6 (24%)

9 (36%)

TLC(cell/mm3)

    

0.59

 <11950 (n = 25)

6 (24%)

6 (24%)

6 (24%)

7 (28%)

 ≥11950 (n = 25)

8 (32%)

4 (16%)

3 (12%)

10 (40%)

ALC(×109/L)

    

0.79

 <1.2 (n = 24)

8 (33.3%)

4 (16.7%)

5 (20.8%)

7 (29.2%)

 ≥1.2 (n = 26)

6 (23.1%)

6 (23.1%)

4 (15.4%)

10 (38.5%)

  1. DFN Duration of febrile neutropenia, HG hemoglobin, TLC Total leukocytic count, Plt platelets, ANC Absolute neutrophilic count, AMC Absolute monocytic count, ALC Absolute lymphocytic count