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Table 5 Relation between demographic, clinical, and biochemical findings and CMV and/or EBV as detected in serum by qualitative PCR assay in leukemic patients

From: Epstein-Barr virus and cytomegalovirus infections and their clinical relevance in Egyptian leukemic pediatric patients

  CMV orEBV alone
n = 19
Both positive
n = 9
Both negative
n = 22
p value
Age     0.61
 ≤6 years (n = 23) 7 (30.4%) 5 (21.7%) 11 (47.8%)
 >6 years (n = 27) 12 (44.4%) 4 (14.8%) 11 (40.7%)
Sex     0.53
 Male (n = 26) 11 (42.3%) 3 (11.5%) 12 (46.2%)
 Female (n = 24) 8 (33.3%) 6 (25%) 10 (41.7%)
Mucositis     0.07
 Yes (n = 22) 7 (31.8%) 7 (31.8%) 8 (36.4%)
 No (n = 28) 12 (42.9%) 2 (7.1%) 14 (50.0%)
Organomegaly     0.72
 Yes (n = 35) 14 (40.0%) 7 (20.0%) 14 (40.0%)
 No (n = 15) 5 (33.3%) 2 (13.3%) 8 (53.4%)
DFN (days)     0.75
 <26.5 (n = 25) 8 (32%) 5 (20%) 12 (48%)
 >26.5 (n = 25) 11 (44%) 4 (16%) 10 (40%)
ANC (×109/L)     0.07
 <0.13 (n = 25) 13 (52%) 2 (8%) 10 (40%)
 ≥0.13 (n = 25) 6 (24%) 7 (28%) 12 (48%)
Plt count (×109/L)     0.27
 <39.5 (n = 25) 7 (28%) 4 (16%) 14 (56%)
 ≥39.5 (n = 25) 12 (48%) 5 (20%) 8 (32%)
Hb (gm/dL)     0.65
 <7.4 (n = 25) 10 (40%) 3 (12%) 12 (48%)
 ≥7.4 (n = 25) 9 (36%) 6 (24%) 10 (40%)
AMC(×109/L)     0.43
 <0.11 (n = 25) 9 (36%) 3 (12%) 13 (52%)
 ≥0.11 (n = 25) 10 (40%) 6 (24%) 9 (36%)
TLC(cell/mm3)     0.57
 <11950 (n = 25) 11 (44%) 5 (20%) 9 (36%)
 ≥11950 (n = 25) 8 (32%) 4 (16%) 13 (52%)
ALC(×109/L)     0.93
 <1.2 (n = 24) 10 (41.7%) 4 (16.7%) 10 (41.7%)
 ≥1.2 (n = 26) 9 (34.6%) 5 (19.2%) 12 (46.2%)
  1. Numerical factors were divided according to their median values
  2. DFN Duration of febrile neutropenia, HG hemoglobin, TLC Total leukocytic count, Plt platelets, ANC Absolute neutrophilic count, AMC Absolute monocytic count, ALC Absolute lymphocytic count